Semaglutide Prefilled Multidose Pen

Patient Information Leaflet

Please read this leaflet carefully before using your Semaglutide pen and keep it for future reference. Consult your doctor, pharmacist, or nurse if you have any questions.

What is Semaglutide?

Semaglutide is a prescription medicine used to improve blood sugar control in adults with type 2 diabetes and to support weight loss in adults with obesity or overweight conditions when combined with a reduced-calorie diet and increased physical activity. It is administered as a once-weekly subcutaneous injection using this prefilled multidose pen.

What GLP is it?

Semaglutide is a GLP-1 (Glucagon-Like Peptide-1) receptor agonist. It mimics the action of the GLP-1 hormone to stimulate insulin release after meals, reduce glucagon levels, slow gastric emptying, and decrease appetite, aiding in blood sugar regulation and weight management.

Anabolic?

Semaglutide is not an anabolic steroid and does not directly promote muscle growth. Its primary function is to enhance metabolic health by improving glucose control and supporting weight loss, which may indirectly improve body composition when paired with exercise and proper nutrition.

Active Ingredient

Semaglutide: Each prefilled multidose pen contains 7 mg of semaglutide in a total volume designed for 240 clicks (approximately 0.02917 mg per click).

Benefits

Improves blood sugar control in adults with type 2 diabetes.
Supports weight loss and weight maintenance in adults with obesity or overweight conditions.
Convenient once-weekly dosing with a prefilled pen.

Instructions for Use

Follow these steps to use your Semaglutide prefilled multidose pen safely and effectively. Always wash your hands before starting.

Prepare Your Pen

Check the pen label to ensure it’s the correct medicine and not expired.
Inspect the Semaglutide medicine through the pen window. It should be clear and colorless. Do not use if it’s cloudy, discolored, or contains particles.
Remove the pen cap.

Attach the Needle (6 Needles Supplied)

Tear off the paper tab from a new needle.
Push the needle straight onto the pen and turn it clockwise until it’s tight.
Pull off the outer needle cap and then the inner needle cap, keeping the needle sterile.

Check the Semaglutide Flow with Each New Pen

Turn the dose selector to 1 click.
Hold the pen with the needle pointing up and gently press the dose button until a drop of liquid appears at the needle tip. This ensures the pen is working. If no liquid appears, repeat up to 3 times. If it still doesn’t work, use a new pen.

Select Your Clicks

The pen delivers up to 69 clicks per injection (approximately 2 mg max per dose). For higher doses, split the injection into two parts (e.g., half now, half immediately after in a different site).
Turn the dose selector to the number of clicks prescribed:
- Week 1 –4 (Start): 9 clicks (0.25 mg)
- Week 5–8 (Increase): 17 clicks (0.50 mg)
- Week 9–12 (Increase): 34 clicks (1 mg)
- Week 12–14 (Increase): 58 clicks (1.7 mg)
- Week 15+ (Maintenance): 69 clicks (2 mg)

Injecting Your Dose

Choose an injection site: abdomen (at least 2 inches from the navel), thigh, or upper arm. Rotate sites weekly.
Clean the site with an alcohol wipe and let it dry.
Insert the needle into your skin at a 90-degree angle.
Press and hold down the dose button until the dose counter reaches 0.
Slowly count to 6 while holding the button to ensure the full dose is delivered.
Remove the needle from your skin.

After Your Injection

Carefully remove the needle from the pen and place it in a sharps container.
Put the pen cap back on the pen to protect it for future use.
Store the pen as directed (see Storage below).

Warning

Do not use if: You or a family member have had medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you’re allergic to semaglutide or any ingredients.
Thyroid cancer risk: Semaglutide caused thyroid tumors in rats. It’s unknown if this happens in humans, but tell your doctor if you notice a lump in your neck, hoarseness, trouble swallowing, or shortness of breath.
Other risks: May cause pancreatitis, low blood sugar (especially with insulin or sulfonylureas), kidney problems, or severe stomach issues. Contact your doctor if you experience severe abdominal pain, vomiting, or unusual symptoms.
Pregnancy and breastfeeding: Tell your doctor if you’re pregnant, planning to become pregnant, or breastfeeding.
Overdose: If you use more than prescribed, seek medical help immediately.

Storage

Store the Semaglutide pen in a refrigerator at 2°C to 8°C (36°F to 46°F) before first use. Do not freeze.
After first use, keep at room temperature below 30°C (86°F) or in the refrigerator, and use within 56 days.
Protect from direct light.
Keep out of reach of children.

Additional Information

Use the pen once weekly, on the same day each week, with or without food.
If you miss a dose, take it within 5 days. If more than 5 days have passed, skip it and resume your next scheduled dose.
Dispose of used needles and pens per local regulations.

This leaflet does not replace advice from your healthcare provider. Contact them with any concerns.

Weight-loss Prescription Semaglutide 7mg Pen