Product Name: Night Surge Pen

Formulation: 2.6 mL pre–filled pen

Clicks per Pen: 240

Total Amount: 10 mg (5 mg CJC-1295+ 5 mg Ipamorelin)

Supplied with: 6 sterile needles (extras available)

Description

Night Surge combines two synergistic growth hormone secretagogues:

CJC-1295 (No DAC): A synthetic tetrasubstituted analog of growth hormone-releasing hormone (GHRH) designed to stimulate the natural release of growth hormone from the pituitary gland. The peptide contains four amino acid substitutions that enhance stability and resistance to enzymatic degradation while maintaining its ability to bind to GHRH receptors. Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂.

Ipamorelin: A selective pentapeptide ghrelin mimetic and growth hormone secretagogue that stimulates growth hormone release while minimizing effects on cortisol and prolactin. Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (Aib = 2-aminoisobutyric acid).

Mechanism of Action

CJC–1295 binds to GHRH receptors on pituitary somatotrophs, stimulating prolonged, pulsatile release of endogenous growth hormone (GH) while preserving physiological feedback regulation. The DAC modification extends its half-life to several days, allowing sustained GH pulses.
Ipamorelin acts as a ghrelin receptor (GHSR-1a) agonist, triggering acute GH release via the pituitary without significant effects on cortisol, prolactin, ACTH, or appetite.

The combination produces additive or synergistic GH pulses: CJC-1295 provides sustained baseline elevation, while Ipamorelin generates sharp nocturnal peaks. This mimics youthful GH secretion patterns, promoting nocturnal tissue repair, protein synthesis, lipolysis, and recovery during sleep.

Indications & Usage

Night Surge is used to support physiological growth hormone release and nocturnal recovery. It is indicated for:

Enhancement of deep restorative sleep and sleep–associated tissue repair
Promotion of muscle recovery, protein synthesis, and connective tissue remodelling
Support for fat metabolism and body composition during rest
Assistance in age–related decline of natural GH secretion and recovery capacity

Contraindications & Warnings

Do not use if you have:

Known hypersensitivity to CJC-1295, Ipamorelin, or any excipient
Active malignancy or history of cancer (GH/IGF-1 axis stimulation concern)
Severe uncontrolled diabetes mellitus or proliferative diabetic retinopathy
Intracranial lesion or pituitary tumor
Pregnancy or breastfeeding
Age under 18 years

Warnings

Use only under medical supervision with periodic monitoring (IGF-1, glucose, HbA1c, clinical parameters).
Not a substitute for standard medical treatment of sleep disorders, metabolic conditions, or recovery needs.
Potential for glucose intolerance, fluid retention, or carpal tunnel symptoms (usually transient).
Discontinue immediately and seek medical attention if severe symptoms occur (e.g., severe headache with visual changes, severe abdominal pain, or signs of allergic reaction).

Dosage & Administration

Subcutaneous injection only.
Standard Dose Range: 400-500 mcg total blend per injection (~200-250 mcg each peptide)
- 400 mcg total≈ 10 clicks
- 500 mcg total≈ 12 clicks
Frequency: Once daily, 5-7 nights per week (e.g., 5 on/2 off for recovery protocols)
Timing: Evening/bedtime (ideally 1-2 hours after last meal, on empty stomach) to align with natural nocturnal GH surge
Cycle Length: 8-16 weeks on (often 12 weeks for sustained protocols), followed by 4 weeks off to maintain pituitary sensitivity

Administration Instructions

Wash hands and prepare a clean surface.
Attach a sterile needle.
Dial the required number of clicks.
Clean injection site (abdomen or thigh) with alcohol swab.
Insert needle at 45-90° angle and inject slowly.
Withdraw needle, dispose safely, and cap the pen.
Rotate injection sites to minimize irritation.
Always inspect solution before use: Do not inject if cloudy, discoloured, or containing particles.

Side Effects

The combination is generally well tolerated. Reported reactions are uncommon and usually mild/transient, including:

Mild injection-site irritation, redness, or itching
Transient headache, light-headedness, or flushing
Temporary water retention or joint stiffness (dose–related)
Rare mild gastrointestinal discomfort or changes in appetite
Rare transient elevation in blood glucose or insulin resistance markers
If any severe or persistent symptoms occur (e.g., severe headache with visual changes, severe abdominal pain, or allergic signs), discontinue use and contact your healthcare provider immediately.

Storage & Handling

Store either in refrigerator (fridge); never freeze or in a cool dry place (≤25-30°C / 77-86°F). Keep pen capped and protected from light and heat.
After first use: Same storage conditions.
Keep out of reach of children.
Discard if expired or solution appears abnormal.

Powered by Precision MSSPT

Peptide Pen formulations set the standard for research peptide delivery in challenging environments. Powered by exclusive MSSPT, each pen combines buffers, antioxidants, and proprietary agents in a compact, user-friendly injector, delivering strict control over pH, light, oxygen, oxidative factors, and moisture even under South Africa’s subtropical variability or the UAE’s extreme desert heat and humidity. This proprietary technology positions Peptide Pen as the premier choice for researchers in these regions: no mixing, no guesswork, and reliable, high-fidelity results despite demanding protocols and climates. Every Peptide Pen is built for exceptional durability, reliability, and performance- providing precision molecular stabilization in every dose, wherever your research takes you.

IMPORTANT NOTICE

This product is not intended to diagnose, treat, cure, or prevent any disease. Statements have not been evaluated by the FDA, SAHPRA, or other authorities. Always consult a licensed healthcare provider before use, especially if pregnant, breastfeeding, under 18, or managing medical conditions.

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